Ugolino da Siena was the most original and accomplished follower of the great Sienese trecento painter Duccio. Among Ugolino's most important commissions was the high altarpiece of Santa Croce, the Franciscan church in Florence. The Last Supper formed part of the predella of the now dismembered altarpiece. The lost central panel of the Madonna and Child was signed by Ugolino da Siena who, along with his father and two brothers, was part of a large workshop assembled to complete the altarpiece.

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