The period from 1400 to 1600 in the Balkan peninsula is defined by increasing Ottoman imperial ambitions. Declining Byzantine power and decades of Ottoman expansion culminate in the capture of Constantinople, capital of the Eastern Roman Empire for over a thousand years, by the Ottomans under Mehmed II in 1453. This event has important artistic repercussions; many artists flee to Europe, taking their skills with them, while others remain, contributing to developments in the Ottoman world. By 1600, following the prosperous reign of Süleyman “the Magnificent,” the region is not only politically unified, but becomes central to an empire which dominates significant parts of three continents (Europe, Asia, and Africa).